Tag: longevity
Senolytics & Clearing โZombie Cellsโ
Senolytics & Clearing โZombie Cellsโ Senescent cells = damaged cells that refuse to die, releasing inflammatory chemicals that accelerate aging. ๐ฌ Natural Senolytics (Zombie Cell Killers): ๐ก How to Use Senolytics:
Autophagy & Cellular Cleanup
What is Autophagy? Autophagy = your bodyโs self-cleaning process that removes damaged cells & proteins. It declines with age, but you can trigger it with: โณ Fasting โ 24-48 hours maximally boosts autophagy. Even time-restricted eating (16:8) helps.๐๏ธโโ๏ธ Exercise โ High-intensity & endurance training ramp up autophagy in muscles & the brain.๐ฆ Polyphenols & Compounds:…
Gut Microbiome & Longevity
Your gut bacteria directly impact inflammation, metabolism, and brain function. Aging is linked to microbial imbalance (dysbiosis), so optimizing gut health is key. โ Longevity-Boosting Foods:Fermented foods: Kefir, yogurt, sauerkraut, kimchiPrebiotics: Garlic, onions, leeks, asparagus, resistant starch (cooked/cooled potatoes, green bananas)Polyphenols: Dark berries, pomegranate, green tea, red wine (moderation) ๐ซ Avoid Gut Disruptors:Ultra-processed foods &…
Hormesis & Longevity
What is Hormesis? Hormesis is the idea that small doses of stress make you stronger by activating longevity pathways (AMPK, sirtuins, FOXO). Key hormetic stressors: ๐ฅ Cold Exposure โ Boosts norepinephrine, metabolism, and resilience. Try cold showers (30 sec – 2 min) or ice baths. ๐ Heat Therapy (Sauna) โ Triggers heat shock proteins (HSPs)…
Tasty and Bad: Two Sides of the Advanced Glycation End Products.
Addition below: New analysis disputes the assumption in the headline. Advanced Glycation End Products (AGEs) are harmful compounds formed when sugars react with proteins or fats in a process called glycation. This happens naturally in the body over time but can also occur when food is cooked at high temperatures (like grilling, frying, or roasting).…
Important article about Vitamin B12 and aging
A recent study published in the Annals of Neurology on February 10, 2025, investigated the relationship between vitamin B12 levels and brain health in older adults. The researchers found that even when vitamin B12 levels are within the normal range, lower concentrations can be linked to subtle brain changes and cognitive issues. Key Findings:Brain Structure…
Alpha-lipoic Acid Review: Anti-Aging, Antioxidant, Anti-inflammatory, and Neuroprotective Effects
Alpha-lipoic acid isย an antioxidant made by the body. It is found in every cell, where it helps turn glucose into energy. Antioxidants attack “free radicals,” waste products created when the body turns food into energy. It is also available as a dietary supplement Alpha-lipoic Acid: An Antioxidant with Anti-aging Properties for Disease Therapy Numerousย in silico,…
Creatine supplementation in older adults can double the amount of strength gained from resistance training.
Creatine monohydrate supplementation provides some anti-sarcopenic benefits for older adults.
Air Pollutants Cause Frailty
Effects of air pollutants exposure on frailty risk: A systematic review and meta-analysis “Meta-analysis indicated that PM2.5ย exposure was significantly associated with frailty assessed by the frailty index… Moreover, solid fuel exposures were significantly associated with an increased risk of frailty assessed by the frailty phenotype … or the frailty index … Exposure to PM2.5ย and solid…