Tag: Glutathione
Glutathione Increases Healthspan and Lifespan.
Glutathione and glutathione-dependent enzymes: From biochemistry to gerontology and successful aging The tripeptide glutathione (GSH), namely γ-L-glutamyl-L-cysteinyl-glycine, is an ubiquitous low-molecular weight thiol nucleophile and reductant of utmost importance, representing the central redox agent of most aerobic organisms. GSH has vital functions involving also antioxidant protection, detoxification, redox homeostasis, cell signaling, iron metabolism/homeostasis, DNA synthesis,…
Glutathione and Probiotic Synergy: The Case for Lactobacillus fermentum ME-3
Glutathione is the body’s most potent intracellular antioxidant, and maintaining its levels is central to healthy aging, detoxification, and immune defense. While glycine and NAC support glutathione synthesis, the probiotic strain Lactobacillus fermentum ME-3 offers a unique biological advantage: it is capable of synthesizing and recycling glutathione inside the body. Direct Glutathione Boost: ME-3 uniquely…
What Could Go Wrong? Radioprotective Strategies & How to Mitigate
Radiation DamageIntroduction: Understanding Radiation RisksRadiation exposure, whether from nuclear accidents, medical scans, air travel, or cosmic rays, can damage DNA, increase cancer risk, and accelerate aging. But not all radiation exposure is equal—low doses might be harmless (or even beneficial, as per hormesis), while high doses can be dangerous. This guide covers radioprotective strategies, including:✔…
Why I’m taking Gly-NAC?
Glutathione (GSH) and its precursors (NAC and glycine) are critical in combating oxidative stress, inflammation, and mitochondrial dysfunction. NAC and glycine supplementation shows promise in improving metabolic, reproductive, cardiovascular, and aging-related health outcomes. Combined supplementation (e.g., GlyNAC) often yields synergistic benefits, particularly in aging and chronic disease contexts. Future research should focus on long-term effects,…