Born to Music: Bio-Hacker’s Diary
Live Long and Prosper!
About
Bio-Hacking Diary, Longevity Protocol, Latest Research Shorts
Staying Alive After 60. For Centenarians and Wannabees.
My Current Bio-Hacking for Longevity
Glycine Promotes Longevity. Branched-Chain Amino Acids (BCAAs) Shorten Your Life.
While glycine supplementation appears to have a positive impact on longevity, excessive intake of BCAAs may have adverse effects.
I resumed taking glycine in January after a 3 months break since October when I run out of stock and had problems with the customs. I just noticed: I feel my face skin has become thicker, smoother and velvety to touch. It’s probably glycine, since I didn’t change anything else. Don’t have ‘before’ and ‘after’ pictures though.
Glycine, mTOR, and Cancer Prevention
More on Glycine
Ketogenic Diet for Heart and Brain : Two Articles
Diet for Optimizing the Glycine/Methionine Ratio
Part 1 One-Carbon Metabolism and Methylation Explainer. Part 2 Glycine-to-Methionine Ratio and Cancer Risk
My Longevity Protocol
Blog
Tales my Mother Told me
I keep adding more stories as I recall them
Latest Research Hot Topics: Most Recent First:
Ketogenic Diet Against Dyslipidemia
Carnosine Against Dementia
Melatonin, Nitric Oxide and Adenosine for Alzheimer’s
Probiotic diet for Alzheimer’s
Nutritional Supplements in Alzheimer’s Disease
Carnivore Diet Benefits and Risks
Keto Does Not Cause Plaque
(But only if you are healthy otherwise)
Klotho: The Anti-Aging Protein and How to Support It
Glutathione and Probiotic Synergy: The Case for Lactobacillus fermentum ME-3
Short-Chain Fatty Acids and Gut Microbiota: Limited but Valuable Energy Contribution
I’m taking several supplements that according to the published research should do me good. Except for multi-vitamins, I’m not taking them in the capsule form. Mostly I dissolve or suspend them in water. Some supplements, like sweet glycine taste good, some taste like nothing, some blah.. Wouldn’t it be nice if they all tasted good?
I’m bothered by this question: Why can’t my senses of taste or smell tell me whether these supplements would be good or bad for me. There is a basis for that idea, a phenomenon called pica, where people (especially pregnant women) crave non-food substances like chalk, clay, or even paint. It’s often linked to mineral deficiencies, particularly calcium or iron. When an animal gets sick it looks up some herb that helps it. Possibly our modern lifestyle got our senses atrophied.
I’m still looking into the literature on that question. As a digression I learned about five basic taste flavors—sweetness, saltiness, bitterness, acidity and umami taste. Learned about new variations, such as kokumi sensation caused by peptide, or chain of amino acids, called glutathione, gamma-GLU-CYS-GLY. Another one is GLU-VAL-GLY. Interesting that all mentioned variation peptides contain glycine, a sweet amino acid I take as a supplement. One also contains cysteine, I also take it in the form of NAC. Kokumi sensation has three components: complexity, mouthflness, and lingeringness. There is also: fat taste.
Some articles already claim these peptides have life extension properties. We are approaching a point of having supplements that are good for you and also taste good! Then the industry will use them in ultra-processed foods. That could make you overeat like what they did with MSG (glutamate). Who knows?
Smell and taste disorders early signs of dementia
If you like the smell of earth you may need more iron.
Taste and Smell in Human Diseases
Seed Oil May Cause Breast Cancer
Creatine Supplementation for Brain in Older Adults
Leucine and Isoleucine: Longevity and Cancer Risk
Sleep Deficiency Causes Brain Atrophy and Alzheimer’s
Understanding Mitochondrial Quality Control
Sugar Causes Gout
Diet Wars: Optimal dietary patterns for healthy aging
Teeth Remineralization Methods: CPP-ACP Cream vs. Fluoride (F)
Fluoride and Its Potential Dangers to the Brain: A Critical Analysis
Optimal Supplement Protocol for Dental & Bone Health
Mitochondrial Health and Antibiotics
Diet Wars: Meat consumption and cancers -Five Contradictory Articles
Everybody is looking for the best diet. But turns out scientists also use intentionally unhealthy diets. Sugar with Butter is one of them. Here’s more:
FYI: Intentionally Bad Diets
FYI: Sulfur Microbial Diet: What It Is and How It Affects Your Health
FYI: The sulfur microbial diet and cancer risk
FYI: Pomegranate Prevents Cancer
Want to Get Fat and Sick? Eat Sugar Together With Butter!
FYI: Is it better to take amino acid supplements with food or alone?
FYI: Food Aversions: Causes and Reasons
FYI: Are Cravings a Sign of Nutrient Deficiency?
Diet Wars: Do People Lie in Questionaries?
Signs of Nutritional Deficiencies and Recommended Supplements
Cooking oil peroxidation causes Alzheimer’s. What to know: Vegetable oils and their Susceptibility to Peroxidation
Senotherapeutics: The Promise of Anti-Aging Medicine
FYI: B12 forms: Methylcobalamin – Cyanocobalamin – Hydroxocobalamin: What to know.
Beauty and Skin: Collagen and Vitamin C Improve Skin Wrinkles
Scoop: Magnesium Fixes Muscle Soreness; Ibuprofen Does Not!
Aches and Pains: Electrical Stimulation for Postherpetic Neuralgia
Live Long and Prosper: Fasting-mimicking diet reduces biological age and disease risk
Diet Wars: Vegetable Oils vs. Animal Fats: The Safety and Health Debate
Aches and Pains: Preventing and Treating Lower Back Pain in Seniors
Beauty and Skin: Top weapons in skin aging
Aches and Pains: Betaine for autoimmune gastritis
Forget Dementia: Four New studies: Keto Wins!
Live Long and Prosper: omega-3, vitamin D and exercise are slowing biological aging
Omega-3 helps. And it helps sick people more than the healthy ones. Ha!
I wonder why – A mystery /s
Live Long and Prosper: Taurine reduces the risk for metabolic syndrome
FYI: Understanding Key Inflammatory Markers
The World is Ending! Micro- and Nano-Element Depletion in Modern Food
Forget Dementia: Vanadium prevents Alzheimer’s Disease?
Aches and Pains: Nail Fungus (Onychomycosis): Why Is It So Hard to Treat?
Your Vision: The Link Between Diet, Metabolism, and Cataract Risk
(More on your vision)
Keto : Ketogenic Diet and Cardiovascular Diseases
Diet Wars: Dietary glycation compounds “danger” – another theory went bust: eat your fries or not, your choice now!
FYI: Mitochondrial Integrated Stress Response (ISRmt) and Its Role in Aging and Longevity – A Simple Summary
FYI: Inflammaging, Cancer, and Autoimmune Diseases: Recent Research
More on Inflammation
More on Mitochondrial Health (Your Cellular Energy)
More on Diet for Longevity
Live Long and Prosper: Nitric Oxide and Human Longevity
My Pictures While Walking Climbing Crawling:
Opinion
How to Lie with Statistics: Navigating Complexity in Multivariate Systems
More:
Maybe: 
Antidepressants Accelerate Dementia (if you believe it)
higher dispensed doses of SSRIs were associated with higher risk for severe dementia. Is the logic flawed?
Walking Climbing: Keep Physically Fit: Frailty Precedes Dementia
More on Brain Fitness
A piece of my latest music piece
Breathe Deep: N-Acetylcysteine (NAC) Treats and Prevents Respiratory Diseases
N-Acetylcysteine (NAC) is a versatile compound with notable applications in respiratory health due to its mucolytic (mucus-thinning), antioxidant, and anti-inflammatory properties. Recent studies have explored its potential benefits across various respiratory conditions.
More on NAC
Two-Edged Iron Sword: Iron Deficiency and Iron Overload in the Elderly
Iron plays a crucial role in various physiological processes, including oxygen transport, DNA synthesis, and electron transport. In the elderly population, maintaining appropriate iron levels is essential, yet it presents unique challenges due to age-related changes in metabolism, dietary intake, and the prevalence of chronic diseases.
More Magnesium Please!
Magnesium-to-calcium ratio ≤0.20 is strongly associated with mortality in patients with severe COVID-19.
Potassium and the Potassium/Sodium Ratio: Electrolytes Matter
More on Minerals
Strengthen Your immune System
A strong immune system is your best defense against flu, COVID-19, and other infections. The key is to optimize nutrition, lifestyle, and targeted supplements to keep your immune system resilient. How?
What is Hormesis:
Ketogenic Diet for Older Adults:
The ketogenic diet presents potential benefits for older adults, particularly in managing and preventing age-related diseases.
Latest on Vitamin C + My Experience with Megadosing C
All three articles highlight vitamin C’s role as a potent antioxidant that helps neutralize free radicals, thereby reducing oxidative stress. This action supports the immune system and may contribute to inhibiting cancer cell growth and mitigating severe infections like COVID-19.
