Excersize Prevents Cancer and Preserves Muscle – two articles
Exercise suppresses tumor growth independent of high fat food intake and associated immune dysfunction Taken together, our data support epidemiological findings showing that exercise suppresses tumor growth independent of BMI, however, our data suggest that high-fat feeding attenuates exercise-mediated immune recognition of tumors. Exercise-Mediated Lowering of Glutamine Availability Suppresses Tumor Growth and Attenuates Muscle Wasting…
Ketogenic Diet Against Dyslipidemia
Metabolic Effects of Ketogenic Diets: Exploring Whole-Body Metabolism in Connection with Adipose Tissue and Other Metabolic Organs The ketogenic diet (KD) is characterized by minimal carbohydrate, moderate protein, and high fat intake, leading to ketosis. It is recognized for its efficiency in weight loss, metabolic health improvement, and various therapeutic interventions. The KD enhances glucose…
Carnosine Against Dementia
The protective role of carnosine against type 2 diabetes-induced cognitive impairment Carnosine, a histidine containing dipeptide, plays a protective role in cognitive diseases due to its antioxidant, anti-inflammation, and anti-glycation properties, all of which may slow the development of neurodegenerative diseases and ischemic injury. Furthermore, carnosine is also involved in regulating glucose and insulin in…
Melatonin, Nitric Oxide and Adenosine for Alzheimer’s
Alzheimer’s disease (AD) is a progressive neurodegenerative disease. The accumulation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles are the key players responsible for the pathogenesis of the disease. The accumulation of Aβ plaques and tau affect the balance in chemical neurotransmitters in the brain. The regulation of melatonin, known for its effectiveness in enhancing…
Nutritional Supplements in Alzheimer’s Disease
https://pubmed.ncbi.nlm.nih.gov/40077790/ Some studies have reported positive effects from specific regimens, such as curcumin (800 mg/day), omega-3 fatty acids (2 g/day), and resveratrol (600 mg/day). Other supplements, like phosphatidylserine (300 mg/day), multinutrient formulations, probiotics, vitamin E (2000 IU/day), and melatonin (3-10 mg/day), also show benefits, though study variability makes conclusions uncertain.
Carnivore Diet Benefits and Risks
Results: The carnivore diet met several NRV thresholds for nutrients such as riboflavin, niacin, phosphorus, zinc, Vitamin B6, Vitamin B12, selenium, and Vitamin A, and exceeded the sodium threshold. However, it fell short in thiamin, magnesium, calcium, and Vitamin C, and in iron, folate, iodine and potassium in some cases. Fibre intake was significantly below recommended…
Keto Does Not Cause Plaque
Plaque Begets Plaque Over a 1-year prospective study of 100 persons exhibiting extreme carbohydrate restriction-induced elevations in LDL-C and ApoB, changes in and baseline levels of ApoB were not associated with changes in noncalcified plaque volume or total plaque score as measured by CCTA. However, baseline CAC and other plaque metrics were positively associated with…
Klotho: The Anti-Aging Protein and How to Support It
Klotho is a hormone-like protein that has garnered attention as a key longevity factor. Originally identified in mice, where its absence led to premature aging, klotho is now recognized as a modulator of multiple aging pathways in humans.Neuroprotection and Cognitive Health: Klotho levels are associated with improved cognition and brain plasticity. It enhances synaptic signaling…
Glutathione Increases Healthspan and Lifespan.
Glutathione and glutathione-dependent enzymes: From biochemistry to gerontology and successful aging The tripeptide glutathione (GSH), namely γ-L-glutamyl-L-cysteinyl-glycine, is an ubiquitous low-molecular weight thiol nucleophile and reductant of utmost importance, representing the central redox agent of most aerobic organisms. GSH has vital functions involving also antioxidant protection, detoxification, redox homeostasis, cell signaling, iron metabolism/homeostasis, DNA synthesis,…