Plaque Begets Plaque

Over a 1-year prospective study of 100 persons exhibiting extreme carbohydrate restriction-induced elevations in LDL-C and ApoB, changes in and baseline levels of ApoB were not associated with changes in noncalcified plaque volume or total plaque score as measured by CCTA. However, baseline CAC and other plaque metrics were positively associated with increases in coronary plaque, supporting the notion that plaque begets plaque but ApoB does not, in this population.