My Approach to Longevity
As a long time reader and follower of the science based approach to health and longevity, here I describe the basis of my current regiment. It may not suit everybody, but works for me. Optimizing Longevity and Health: The Synergistic Benefits of Glycine, NAC, Taurine, Creatine, Vitamins C & D, Niacin, and Magnesium with a…
Leucine and Isoleucine: Longevity and Cancer Risk
Leucine and isoleucine are two essential branched-chain amino acids (BCAAs) that play crucial roles in metabolism, muscle maintenance, and overall health. However, their impact on longevity and cancer risk is complex and depends on dietary intake, metabolic status, and individual health conditions. Leucine: A Double-Edged Sword Longevity BenefitsMuscle Maintenance & Anti-Sarcopenia: Leucine is well-known for…
Sleep deficiency cause brain atrophy and Alzheimer’s
Conclusions:Sleep deficiency is associated with the atrophy of the inferior parietal region, which is observed in early AD. https://jcsm.aasm.org/doi/10.5664/jcsm.11630
Optimal dietary patterns for healthy aging
https://pubmed.ncbi.nlm.nih.gov/40128348/ Here, using longitudinal questionnaire data from the Nurses’ Health Study (1986-2016) and the Health Professionals Follow-Up Study (1986-2016), we examined the association of long-term adherence to eight dietary patterns and ultraprocessed food consumption with healthy aging, as assessed according to measures of cognitive, physical and mental health, as well as living to 70 years…
Optimal Supplement Protocol for Dental & Bone Health 🦷💪
A strong supplement strategy can support tooth remineralization, gum health, and bone strength, especially for elderly individuals who are at higher risk of enamel loss, cavities, and osteoporosis. Below is a biohacker-approved protocol with key supplements, dosages, and benefits. 1. Core Minerals for Enamel & Bone Strength ✅ Calcium (Hydroxyapatite or Citrate) – 500–1,000 mg/day🔹…
Teeth Remineralization Methods: CPP-ACP Cream vs. Fluoride (F)
Tooth remineralization is a critical process for repairing early-stage decay, strengthening enamel, and preventing cavities. Two of the most well-researched remineralization agents are Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) and Fluoride (F). Both have unique mechanisms and benefits, making them essential tools in dental health. 1. Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) Cream 🔬 How It Works:CPP-ACP…
Ketogenic Diet Prevents Brain Aging
“Importantly, we find that administering ketones, which can fuel neurons while bypassing insulin resistance, reverses brain aging effects. However, this intervention is only effective when provided early enough for neurons to remain viable. “ “Consistent with these results, an interventional study of 101 participants shows that ketones exhibit robust effects in restabilizing brain networks, maximized from…
Mitochondrial Health and Antibiotics
Antibiotics are lifesaving medications, but their impact on mitochondrial health is a growing area of concern. Since mitochondria evolved from ancient bacteria (endosymbiotic theory), some antibiotics unintentionally target mitochondrial function, leading to energy deficits, oxidative stress, and long-term metabolic consequences. How Antibiotics Affect Mitochondria 1. Mitochondrial Protein Synthesis Inhibition 2. Increased Oxidative Stress 3. Mitochondrial…
What is NAD+ (Nicotinamide Adenine Dinucleotide)
NAD+ is an important coenzyme involved in the transport high-energy electrons to the electron transport chain in aerobic respiration. Aerobic respiration is the process by which the majority of the body’s energy (ATP) is produced. Aging & Longevity Focus – NAD+ levels decline with age, and research on boosting NAD+ for longevity and cellular health has…
Five Contradictory Articles:
The Devil is in the Details? Association of meat consumption with the risk of gastrointestinal cancers: a systematic review and meta-analysis PubMed, EmBase, and the Cochrane library databases were searched systematically for eligible studies that investigated the relation between meat consumption and the risk of developing gastrointestinal cancers, including esophageal cancer (EC), gastric cancer (GC),…