The Neuroprotective Effects of Agmatine on Parkinson’s Disease: Focus on Oxidative Stress, Inflammation and Molecular Mechanisms

Agmatine (AGM), a naturally occurring polyamine derived from L-arginine, has shown significant potential for neuroprotection in Parkinson’s Disease (PD) due to its multifaceted biological activities, including antioxidant, anti-inflammatory, and anti-apoptotic effects. … …This review highlights agmatine’s promising therapeutic potential in PD management, suggesting that it could offer both symptomatic relief and neuroprotective benefits, thereby modifying the disease course and improving the quality of life for patients.